2. Signaling Pathways
  3. GPCR/G Protein
  4. Protease Activated Receptor (PAR)
  5. PAR4 Isoform
  6. PAR4 Antagonist

PAR4 Antagonist

PAR4 Antagonists (4):

Cat. No. Product Name Effect Purity
  • HY-19837
    BMS-986120
    		Antagonist 98.54%
    BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 (PAR4) antagonist, with IC50s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatelet effects.
  • HY-P1263A
    tcY-NH2 TFA
    		Antagonist 99.72%
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology.
  • HY-163504
    PAR4 antagonist 5
    		Antagonist
    PAR4 antagonist 5 (compound 1) is a PAR4 antagonist with an IC50 less than 20 μM and potent anti-platelet aggregation activity. PAR4 antagonist 5 can be used for research of thrombosis disease .
  • HY-19973
    ML354
    		Antagonist
    ML354 is a selective PAR4 antagonist with an IC50 of 140 nM.